STUDIES ON CORRELATED MUTATIONS ALGORITHMS OF PROTEINS PROVIDING STRUCTURAL, SPATIAL, AND ALLOSTERY INFORMATION FROM MULTIPLE SEQUENCE ALIGNMENTS

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Kreth, K. (2013). STUDIES ON CORRELATED MUTATIONS ALGORITHMS OF PROTEINS PROVIDING STRUCTURAL, SPATIAL, AND ALLOSTERY INFORMATION FROM MULTIPLE SEQUENCE ALIGNMENTS. Unc Charlotte Electronic Theses And Dissertations.
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Abstract

Proteins provide innumerable cellular functions and benefits for all kingdoms in the domains of life. Advancements in the high throughput collection and analysis of proteins have led to ever-deeper understanding of biological pathways, evolution, and coding biases. There has been a renaissance of the study of proteins using new approaches that are largely possible because of the amount of data now available for analysis. The research in this dissertation investigates some of the new techniques available in this field, to find the limitations of these techniques as well as improve upon them.

Details
Author

Kreth, Kyle

Title

STUDIES ON CORRELATED MUTATIONS ALGORITHMS OF PROTEINS PROVIDING STRUCTURAL, SPATIAL, AND ALLOSTERY INFORMATION FROM MULTIPLE SEQUENCE ALIGNMENTS

Physical Description

1 online resource (98 pages) : PDF

Date

2013

Degree Granting Institution

University of North Carolina at Charlotte

Abstract

Proteins provide innumerable cellular functions and benefits for all kingdoms in the domains of life. Advancements in the high throughput collection and analysis of proteins have led to ever-deeper understanding of biological pathways, evolution, and coding biases. There has been a renaissance of the study of proteins using new approaches that are largely possible because of the amount of data now available for analysis. The research in this dissertation investigates some of the new techniques available in this field, to find the limitations of these techniques as well as improve upon them.

Genre

doctoral dissertations

Subjects--Topics

Bioinformatics

Degree

Ph.D.

Subject Area

Information Technology

Advisor(s)

Fodor, Anthony

Committee Members

Jacobs, Donald
Livesay, Dennis
Saydam, Cem
Houston, Evan

Degree Note

Thesis (Ph.D.)--University of North Carolina at Charlotte, 2013.

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Rights Holder Information

Copyright is held by the author unless otherwise indicated.

Identifier

Kreth_uncc_0694D_10521

Permalink

http://hdl.handle.net/20.500.13093/etd:836