Search results
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Title
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Hepatic Stellate Cell Transdifferentiation: Pro-fibrogenic Effectors
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Author
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Lakner, Ashley
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Date Created
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2011
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Description
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Hepatic fibrosis is a significant cause of morbidity and mortality worldwide and can be described as exacerbated wound-healing marked by excessive deposition of extracellular matrix components, predominantly type I collagen. Chronic injury stimula...
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Title
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Role of Nonmuscle Myosin II in Hepatic Stellate Cell Activation
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Author
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Moore, Cathy
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Date Created
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2009
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Description
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The hepatic stellate cell (HSC) plays a pivotal role in the development of hepatic fibrosis. Regulation of liver microcirculation is a complex system where blood flow is under systemic and sinusoidal control. Upon a fibrogenic stimulus, quiescent ...