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Loss of Skeletal Muscle PKC Theta Protects Against The Pathogenesis of Insulin Resistance
Title
Loss of Skeletal Muscle PKC Theta Protects Against The Pathogenesis of Insulin Resistance
Author
Peck, Bailey
Date Created
2016
Description
Skeletal muscle is a primary regulator of glucose homeostasis, accounting for the majority of post-prandial glucose disposal. However states of skeletal muscle insulin-resistance result in severely attenuated glucose uptake and consequently hyperg...
Notch Serves as a Molecular Brake on Myogenesis, Protein Synthesis, and Growth in Skeletal Muscle
Title
Notch Serves as a Molecular Brake on Myogenesis, Protein Synthesis, and Growth in Skeletal Muscle
Author
Huot, Joshua
Date Created
2018
Description
Aging can be accompanied by aggressive loss of muscle mass (sarcopenia) and is a primary prognosticator for the reduced capacity of the elderly to accomplish basic activities of daily living. Several mechanisms within skeletal muscle lead to devel...
Notch Serves as a Molecular Brake on Myogenesis, Protein Synthesis, and Growth in Skeletal Muscle
Title
Notch Serves as a Molecular Brake on Myogenesis, Protein Synthesis, and Growth in Skeletal Muscle
Author
Huot, Joshua
Date Created
2018
Description
Aging can be accompanied by aggressive loss of muscle mass (sarcopenia) and is a primary prognosticator for the reduced capacity of the elderly to accomplish basic activities of daily living. Several mechanisms within skeletal muscle lead to devel...
The Role of MicroRNA-26a In Skeletal Muscle Insulin Signaling
Title
The Role of MicroRNA-26a In Skeletal Muscle Insulin Signaling
Author
Petrocelli, Jonathan
Date Created
2018
Description
Chronic saturated fatty acid exposure causes skeletal muscle cells to develop insulin resistance, which contributes to the pathogenesis of type 2 diabetes mellitus. Recently, microRNAs have been viewed as novel molecules that contribute to the reg...