Search results | J. Murrey Atkins Library

Title: CHARACTERIZING NEXT-GENERATION SEQUENCING (NGS) PLATFORMS FOR MULTIPLEXED BIOSENSING AND APTAMER DISCOVERY: G-QUADRUPLEX APTAMERS AS A CASE STUDY
Author: Patil, Sushant
Date Created: 2016
Description: Aptamers are single-stranded DNA or RNA molecules forming unique three dimensional structures that can bind to their targets (generally proteins or metabolites or other nucleic acids) with high specificity and affinity. Screening for aptamers requ...

Title: CHARACTERIZING NEXT-GENERATION SEQUENCING (NGS) PLATFORMS FOR MULTIPLEXED BIOSENSING AND APTAMER DISCOVERY: G-QUADRUPLEX APTAMERS AS A CASE STUDY
Author: Patil, Sushant
Date Created: 2016
Subjects--Topical: Molecular biology, Bioinformatics, Biochemistry
Description: Aptamers are single-stranded DNA or RNA molecules forming unique three dimensional structures that can bind to their targets (generally proteins or metabolites or other nucleic acids) with high specificity and affinity. Screening for aptamers requ...

Title: ENGINEERED WATER REPELLENCY FOR INFILTRATION CONTROL IN COAL FLY ASH
Author: Feyyisa, Jenberu
Date Created: 2017
Description: In 2014 approximately 47% of the 190 million short tons of coal combustion product (CCP) was recycled. As a construction material, coal fly ash (CFA) finds considerable use as a partial replacement for Portland cement, as structural fill, and as a...

Title: ENGINEERED WATER REPELLENCY FOR INFILTRATION CONTROL IN COAL FLY ASH
Author: Feyyisa, Jenberu
Date Created: 2017
Description: In 2014 approximately 47% of the 190 million short tons of coal combustion product (CCP) was recycled. As a construction material, coal fly ash (CFA) finds considerable use as a partial replacement for Portland cement, as structural fill, and as a...

Title: ENGINEERED WATER REPELLENCY FOR INFILTRATION CONTROL IN COAL FLY ASH
Author: Feyyisa, Jenberu
Date Created: 2017
Subjects--Topical: Civil engineering, Environmental engineering
Description: In 2014 approximately 47% of the 190 million short tons of coal combustion product (CCP) was recycled. As a construction material, coal fly ash (CFA) finds considerable use as a partial replacement for Portland cement, as structural fill, and as a...

Title: INTERLEUKIN-2 IN AQUEOUS AND LIPID ENVIRONMENTS: UNDERSTANDING MOLECULAR INTERACTIONS THAT IMPACT PHARMACEUTICAL FORMULATION DEVELOPMENT
Author: Vrikkis, Regina
Date Created: 2013
Description: The continued development of pharmaceutical recombinant proteins as therapeutics necessitates a full understanding of the biomolecular interactions impacting structural and functional protein stability within different environments. Two such envir...

Title: INTERLEUKIN-2 IN AQUEOUS AND LIPID ENVIRONMENTS: UNDERSTANDING MOLECULAR INTERACTIONS THAT IMPACT PHARMACEUTICAL FORMULATION DEVELOPMENT
Author: Vrikkis, Regina
Date Created: 2013
Subjects--Topical: Mechanical engineering, Biomedical engineering, Pharmacy--Research
Description: The continued development of pharmaceutical recombinant proteins as therapeutics necessitates a full understanding of the biomolecular interactions impacting structural and functional protein stability within different environments. Two such envir...

Title: INVESTIGATING THE ROLE OF NEWLY DESCRIBED CYTOSOLIC PATTERN RECOGNITION RECEPTORS IN PROTECTIVE HOST RESPONSES TO NEUROTROPIC VIRUSES
Author: Crill, Emma
Date Created: 2014
Description: The importance of the effector functions performed by glial cells, the resident cells of the CNS possessing immune functions, in abrogating potentially fatal neurotropic viral infections have only recently begun to gain appreciation. These effecto...

Title: INVESTIGATING THE ROLE OF NEWLY DESCRIBED CYTOSOLIC PATTERN RECOGNITION RECEPTORS IN PROTECTIVE HOST RESPONSES TO NEUROTROPIC VIRUSES
Author: Crill, Emma
Date Created: 2014
Description: The importance of the effector functions performed by glial cells, the resident cells of the CNS possessing immune functions, in abrogating potentially fatal neurotropic viral infections have only recently begun to gain appreciation. These effecto...

Title: INVESTIGATING THE ROLE OF NEWLY DESCRIBED CYTOSOLIC PATTERN RECOGNITION RECEPTORS IN PROTECTIVE HOST RESPONSES TO NEUROTROPIC VIRUSES
Author: Crill, Emma
Date Created: 2014
Subjects--Topical: Immunology, Virology
Description: The importance of the effector functions performed by glial cells, the resident cells of the CNS possessing immune functions, in abrogating potentially fatal neurotropic viral infections have only recently begun to gain appreciation. These effecto...

Title: Intracellular pattern recognition receptors underlie inflammatory responses of glial cells to central nervous system pathogens
Author: Sterka, David
Date Created: 2009
Description: There is growing appreciation that the resident glial cells of the CNS, in particular microglia and astrocytes, are important participants in the generation of inflammation during brain infection. However, the mechanisms by which these cell types ...

Title: Intracellular pattern recognition receptors underlie inflammatory responses of glial cells to central nervous system pathogens
Author: Sterka, David
Date Created: 2009
Subjects--Topical: Cytology
Description: There is growing appreciation that the resident glial cells of the CNS, in particular microglia and astrocytes, are important participants in the generation of inflammation during brain infection. However, the mechanisms by which these cell types ...

Title: Long-term study of changes in microbiota in a Cystic Fibrosis patient
Author: Stokell, Joshua
Date Created: 2013
Description: Application of culture-independent techniques have revealed the presence of more types of bacteria than were previously thought, which led to the current description of Cystic Fibrosis (CF) being a polymicrobial disease. We know this polymicrobial...

Title: Long-term study of changes in microbiota in a Cystic Fibrosis patient
Author: Stokell, Joshua
Date Created: 2013
Subjects--Topical: Biology, Microbiology
Description: Application of culture-independent techniques have revealed the presence of more types of bacteria than were previously thought, which led to the current description of Cystic Fibrosis (CF) being a polymicrobial disease. We know this polymicrobial...

Title: MICRO- TO MACROSCALE MODELING OF DRINKING WATER TREATMENT AND DISTRIBUTION
Author: Polaczyk, Amy
Date Created: 2010
Description: Models are valuable tools that can provide quantitative insight into a process or system, but must to be kept simple to remain meaningful. In this dissertation, three separate drinking water research projects were completed using numerical modelin...

Title: MICRO- TO MACROSCALE MODELING OF DRINKING WATER TREATMENT AND DISTRIBUTION
Author: Polaczyk, Amy
Date Created: 2010
Subjects--Topical: Environmental engineering, Environmental sciences
Description: Models are valuable tools that can provide quantitative insight into a process or system, but must to be kept simple to remain meaningful. In this dissertation, three separate drinking water research projects were completed using numerical modelin...

Title: MUC1 MEDIATED SIGNALING IN PANCREATIC DUCTAL ADENOCARCINOMA
Author: Grover, Priyanka
Date Created: 2019
Description: In 2019, Pancreatic Cancer (PC) is the 3rd leading cause of cancer-related deaths in the USA with 94% dying within 5 years of diagnosis. 90% of PC is Pancreatic Ductal Adenocarcinoma (PDA), of which >80% overexpress a hypo-glycosylated form the me...

Title: MUC1 MEDIATED SIGNALING IN PANCREATIC DUCTAL ADENOCARCINOMA
Author: Grover, Priyanka
Date Created: 2019
Subjects--Topical: Biology
Description: In 2019, Pancreatic Cancer (PC) is the 3rd leading cause of cancer-related deaths in the USA with 94% dying within 5 years of diagnosis. 90% of PC is Pancreatic Ductal Adenocarcinoma (PDA), of which >80% overexpress a hypo-glycosylated form the me...

Title: NOVEL ROLES OF MICRORNAS IN HEPATITIS C
Author: Sendi, Hossein
Date Created: 2013
Description: Approximately, 170 million people are infected by hepatitis C virus (HCV) worldwide, and of these, nearly 85% will develop chronic hepatitis C (CHC). Despite finding new anti-viral treatment that increase response rate from 45 % to 65-70 %, invest...

Title: NOVEL ROLES OF MICRORNAS IN HEPATITIS C
Author: Sendi, Hossein
Date Created: 2013
Subjects--Topical: Virology, Biology
Description: Approximately, 170 million people are infected by hepatitis C virus (HCV) worldwide, and of these, nearly 85% will develop chronic hepatitis C (CHC). Despite finding new anti-viral treatment that increase response rate from 45 % to 65-70 %, invest...