Search results
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Title
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DE NOVO PREDICTION OF CIS-REGULATORY MODULES IN EUKARYOTIC ORGANISMS
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Author
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Niu, Meng
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Date Created
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2014
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Description
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Gene regulation networks (GRNs) are the bases for virtually all biological processes. To gain a global understanding of GRNs encoded in a genome, we first need to identify in all the cis-regulatory elements (CREs) recognized by transcription facto...
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Title
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DE NOVO PREDICTION OF CIS-REGULATORY MODULES IN EUKARYOTIC ORGANISMS
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Author
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Niu, Meng
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Date Created
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2014
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Subjects--Topical
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Bioinformatics
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Description
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Gene regulation networks (GRNs) are the bases for virtually all biological processes. To gain a global understanding of GRNs encoded in a genome, we first need to identify in all the cis-regulatory elements (CREs) recognized by transcription facto...
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Title
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Evolution and dynamics of transcriptional regulation in bacteria
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Author
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Li, Shan
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Date Created
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2013
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Description
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Although transcription is one of the most important biological functions of cells, our understanding of its regulation is still limited. In this dissertation, we have studied the transcriptional regulation in prokaryotes in three aspects. First, w...
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Title
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Evolution and dynamics of transcriptional regulation in bacteria
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Author
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Li, Shan
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Date Created
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2013
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Subjects--Topical
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Computer science, Statistics, Bioinformatics
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Description
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Although transcription is one of the most important biological functions of cells, our understanding of its regulation is still limited. In this dissertation, we have studied the transcriptional regulation in prokaryotes in three aspects. First, w...
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Title
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Prediction of Cis-regulatory Modules in Genomes
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Author
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Ni, Pengyu
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Date Created
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2020
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Description
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Annotating all cis-regulatory modules (CRMs) and constituent transcription factor (TF) binding sites (TFBSs) in genomes is essential to understand genome functions, however, the task remains highly challenging. In this dissertation, we first devel...
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Title
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Prediction of Cis-regulatory Modules in Genomes
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Author
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Ni, Pengyu
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Date Created
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2020
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Subjects--Topical
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Bioinformatics
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Description
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Annotating all cis-regulatory modules (CRMs) and constituent transcription factor (TF) binding sites (TFBSs) in genomes is essential to understand genome functions, however, the task remains highly challenging. In this dissertation, we first devel...
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Title
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UNDERSTANDING GENOME-WIDE GENE REGULATION IN PROKARYOTES USING OMICS DATA
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Author
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Seyedi Tabari, Seyed Ehsan
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Date Created
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2016
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Description
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Gene annotation is a critical step for understanding functions of genomes and host organisms. However, accurately annotating thousands of sequenced genomes can be a challenging task. Further, although gene transcriptional regulation is crucial for...
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Title
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UNDERSTANDING GENOME-WIDE GENE REGULATION IN PROKARYOTES USING OMICS DATA
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Author
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Seyedi Tabari, Seyed Ehsan
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Date Created
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2016
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Subjects--Topical
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Bioinformatics, Information science, Biometry
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Description
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Gene annotation is a critical step for understanding functions of genomes and host organisms. However, accurately annotating thousands of sequenced genomes can be a challenging task. Further, although gene transcriptional regulation is crucial for...
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Title
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Understanding gene transcriptional regulation at single cell resolution
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Author
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Xu, Chen
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Date Created
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2015
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Description
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The recent advance of single-cell technologies has provided an unprecedented opportunity to bring new insights into many complex biological phenomena, such as the regulation of cell differentiation in a multi-cellular organism and cell-to-cell var...
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Title
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Understanding gene transcriptional regulation at single cell resolution
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Author
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Xu, Chen
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Date Created
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2015
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Subjects--Topical
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Bioinformatics
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Description
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The recent advance of single-cell technologies has provided an unprecedented opportunity to bring new insights into many complex biological phenomena, such as the regulation of cell differentiation in a multi-cellular organism and cell-to-cell var...