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Redistribution of flexibility in stabilizing antibody fragment mutants follows Le Chatelier's principle
Title
Redistribution of flexibility in stabilizing antibody fragment mutants follows Le Chatelier's principle
Author
Jacobs, Donald J., Li, Tong, Livesay, Dennis R.
Date Created
2014
Subjects--Topical
Immunoglobulins, Biology
Description
Le Chatelier's principle is the cornerstone of our understanding of chemical equilibria. When a system at equilibrium undergoes a change in concentration or thermodynamic state (i.e., temperature, pressure, etc.), La Chatelier's principle states t...